VISDB Viral Integration Site DataBase

VIS ID

TVIS10010732

Fusion event

HBV-SPAG16 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2821

Orient

+

Integrated sequence

TAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCA| |CCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGA

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

214254383/213389659 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4713-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-6507-3p ; hsa-mir-6828-5p ; hsa-mir-651-3p ; hsa-mir-3662

Nearest miRNA

hsa-mir-10b/Upstream/463323; hsa-mir-1244-1/Downstream/368408;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/104957, chr2-CpG: 110/Downstream/1419612

Upstream sequence

aaaaagtccaatccaaaaaaggactttaataacacatttctagattgaagatatataaatggtaaagtacatgaaaagatgcttaacatcattaatcatt

Downstream sequence

aaggaaatacaaatcaaaactgcagtagggtatcacttcagactaataagggtggtttccattaaaaacaaaaagaaagctggtgaggacataagttaat