Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010776
Fusion event
HBV-WDR49 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1803
Orient
-
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |CGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
End
167242474/167524686 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/3353130; hsa-mir-1224/Downstream/1027168;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/144276, chr3-CpG: 37/Downstream/209902
Upstream sequence
ttgtgatgagctgagatcacaccattgcactccagcctgggtgacaagagtgaaattccgtctaaaaaaaaaaaaaaaaaaaaaaaaaaatgtacctgtt
Downstream sequence
gtaaggtttgtcaaagatcagatggttgtaggtgtgtggtgttatttatgaggcctctgttctattccattggtctctttatctgttttggtaccagtac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.