WDR49 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010777
Fusion event
HBV-WDR49 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1625
Orient
+
Integrated sequence
GCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGA| |ACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTT
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
167242475/167524687 (Hg38)
End
167242475/167524687 (Hg38)
Orient
-
Location type
Intronic
Target gene
WDR49
Nearest miRNA
hsa-let-7g/Upstream/3353131; hsa-mir-1224/Downstream/1027167;
Nearest TSS
ENST00000440867/Upstream/45683; ENST00000472941/Downstream/6502;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/144277, chr3-CpG: 37/Downstream/209901
Upstream sequence
tattagtcagggttttccagatcaacagaacaaataggatgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtgtgtgtgtgtctgtagagagagag
Downstream sequence
taaggtttgtcaaagatcagatggttgtaggtgtgtggtgttatttatgaggcctctgttctattccattggtctctttatctgttttggtaccagtacc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate