Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010785
Fusion event
HBV-MYRIP integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
680
Orient
-
Integrated sequence
CTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTT| |ACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATC
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
Start
End
40017446/39975955 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/837689; hsa-let-7g/Downstream/4138257;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/165626, chr3-CpG: 88/Downstream/333411
Upstream sequence
GTGTGGCTCTAAAGGAACATCTGACCAGGTTCCTGGGGAACCAGGGCCATGGGAGGAAGAAGGGACTCTTCTCCCATGAGAAGGGCCTGGAGATGCAGGG
Downstream sequence
acctagacaataccattcaggacataggcatgggcaaggacttcatgtctaaaacaccaaaagcaatggcaacaaaagccaaaattgacaaatgggttct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.