VISDB Viral Integration Site DataBase

VIS ID

TVIS10010789

Fusion event

HBV-EOGT integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2192

Orient

+

Integrated sequence

AACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTT| |CAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCA

Chromosome

chr3

Cytoband

p14.1

Reference genome

Start

End

69063363/69014212 (Hg38)

Orient

+

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-9-5p ; hsa-mir-132-3p ; hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-599 ; hsa-mir-548aw ; hsa-mir-4276 ; hsa-mir-3161 ; hsa-mir-137 ; hsa-mir-4766-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-3908 ; hsa-mir-425-5p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-944 ; hsa-mir-3121-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-301b-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-5007-3p ; hsa-mir-4261 ; hsa-mir-205-3p ; hsa-mir-3688-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-6512-5p ; hsa-mir-4694-3p ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-2052 ; hsa-mir-223-5p ; hsa-mir-297 ; hsa-mir-3680-3p ; hsa-mir-4307 ; hsa-mir-450b-5p ; hsa-mir-4520-5p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-567 ; hsa-mir-574-5p ; hsa-mir-6867-5p

Nearest miRNA

hsa-let-7g/Upstream/1788685; hsa-mir-12124/Downstream/34746;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/173, chr3-CpG: 39/Downstream/37858

Upstream sequence

tttttctttaattagaactctttcatacattttgatagagaactatcacacacacgtaacacatatagacacacagacatacagacttacagaacagaca

Downstream sequence

TTGGAGTCCACACACATTTTAAAAGCAGTATAGTTTTACCTATCCGTAAACTCATCAAGTTCAAATGCTACTCTGTGGAGTTTAATTTTTATGGTTTTGT