VISDB Viral Integration Site DataBase

VIS ID

TVIS10010796

Fusion event

HBV-DNAJB14 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2165

Orient

-

Integrated sequence

TCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTA| |TGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCT

Chromosome

chr4

Cytoband

q23

Reference genome

Start

End

100847582/99926425 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-30c-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-1284 ; hsa-mir-376c-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-187-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-302f ; hsa-mir-3689a-5p ; hsa-mir-3689b-5p ; hsa-mir-3689e ; hsa-mir-3689f ; hsa-mir-3934-5p ; hsa-mir-500a-5p ; hsa-mir-501-5p ; hsa-mir-5089-3p ; hsa-mir-5093 ; hsa-mir-548a-3p ; hsa-mir-548ar-3p ; hsa-mir-548az-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548v ; hsa-mir-552-3p ; hsa-mir-5582-3p ; hsa-mir-875-3p

Nearest miRNA

hsa-mir-12113/Upstream/928965; hsa-mir-1243/Downstream/1314370;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/272928, chr4-CpG: 68/Downstream/19746

Upstream sequence

tccactccattccattccataccattccaccaaaattgattgcatgttattccattccattccattccattcctttccactcgggttgattccattccat

Downstream sequence

GAAGAGAAGCAGTTAATAGAAGTGAAACAGACTGTGAGACAAGGTGGAGAGGTACGAATATGGCAGACACTACCTGAATGCAAAAAATAAAAGGTAAATT