Basic Information
VIS ID
TVIS10010798
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1945
Orient
-
Integrated sequence
TCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGT| |TACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTG
Host Sequence
Chromosome
chr4
Cytoband
q28.1
Reference genome
End
126862012/125940857 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/433550; hsa-mir-1305/Downstream/17402603;
Nearby gene
MIR2054(-433550) ; INTU(+1692075) ;
Upstream sequence
tccaccaaagttgattgcatgttattccattccattccattccatttcattcaattccattccattccattcctttccactcgggttgattccattccat
Downstream sequence
gattccccagattcccctgtcctttgctaatggagaacagcttcccATTTCCTTAAACAGGGCAGAACAATCACATATGACATTTGTCCTCATTAATATC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate