Basic Information
VIS ID
TVIS10010808
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1582
Orient
-
Integrated sequence
TCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGT| |GCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAA
Host Sequence
Chromosome
chr4
Cytoband
p13
Reference genome
End
43198570/43196553 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/2694434; hsa-mir-1243/Downstream/4456116;
Nearby gene
GRXCR1(-165895) ; KCTD8(+977350) ;
Upstream sequence
TGACTAAATCCCATCCACAGCATTACCCACAGAACAAGATTGGAGAAAGATTATCCATTAAAGAGAGAGGGCATTGCTATTATGGCTTTTGAAGACTATA
Downstream sequence
tgtgttcctggtggtctttgattggaCTTTGCTCTTTAGACAATTATACTAAAGTTAGTTCTATGACTGTGTTATTTGAAACTTTGAGTTGGAGAGTAAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate