Fusion event
HBV-chr4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|Polymerase|
Integrated sequence
TCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGT| |GCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAA
End
43198570/43196553 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/2694434; hsa-mir-1243/Downstream/4456116;
Upstream sequence
TGACTAAATCCCATCCACAGCATTACCCACAGAACAAGATTGGAGAAAGATTATCCATTAAAGAGAGAGGGCATTGCTATTATGGCTTTTGAAGACTATA
Downstream sequence
tgtgttcctggtggtctttgattggaCTTTGCTCTTTAGACAATTATACTAAAGTTAGTTCTATGACTGTGTTATTTGAAACTTTGAGTTGGAGAGTAAT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.