Fusion event
HBV-chr4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT
End
64979906/64114188 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/3191504; hsa-mir-1243/Downstream/2162636;
Upstream sequence
CAGAAGCTAGAGAGGGGCACAATCAAATTTGATGCTAGAAGGCAAATTTTCATTCAGATTCTTATGtgtggtagatggcaaaaatggccacgaattcttc
Downstream sequence
AAGTATTTTAGGAGAAAACATATGAGAGATTAGGAAGCTTCTTTTAGCTCTTTCTTGATATGCTTTTTGATATCGTGGTCACAGAAAAGGCATCCTGGCT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.