Fusion event
HBV-TERT integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|Polymerase|
Integrated sequence
GGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCG| |TGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTT
End
1295526/1295411 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-4635/Upstream/232437; hsa-mir-10397/Downstream/13899;
Nearest cancer related gene
Upstream sequence
aggcaggagaattgcttgaacctgggaggcagaggttgcagtgagccgagactgcgccgttgcactccagcctatgcaataagagcgaaactccgtctca
Downstream sequence
CCTAGGCTGTGGGGTAACCCGAGGGAGGGGCCATGATGTGGAGGCCCTGGGAACAGGTGCGTGCGGCGACCCTTTGGCCGCTGGCCTGATCCGGAGACCC
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.