VISDB Viral Integration Site DataBase

VIS ID

TVIS10010846

Fusion event

HBV-FNIP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2210

Orient

+

Integrated sequence

CCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTT| |TCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAAT

Chromosome

chr5

Cytoband

q31.1

Reference genome

Start

End

131018476/131682783 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-18a-3p ; hsa-mir-30d-5p ; hsa-mir-92a-3p ; hsa-let-7a-5p ; hsa-mir-136-5p ; hsa-mir-379-3p ; hsa-mir-493-5p ; hsa-mir-382-5p ; hsa-mir-218-5p ; hsa-mir-223-5p ; hsa-mir-4719 ; hsa-mir-511-3p ; hsa-mir-489-3p ; hsa-mir-137 ; hsa-mir-363-3p ; hsa-mir-92b-3p ; hsa-mir-367-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5096 ; hsa-mir-5687 ; hsa-mir-627-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4773 ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23c ; hsa-mir-6516-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-455-3p ; hsa-mir-203b-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6499-3p ; hsa-mir-767-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4459

Nearest miRNA

hsa-mir-10397/Upstream/2285636; hsa-mir-103a-1/Downstream/535066;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/46971, chr5-CpG: 127/Downstream/113453

Upstream sequence

AGACTGATAATCTGTTTTATTTGTCTATCAATCAAAGGTGCCAGTTTTAGAAAACATGTTCACTTCTTCCAGCTTTGAAAACAAAGTTAAACTAAAGCAA

Downstream sequence

GTGCCCTATCATTCAATGGTAAGAAAAGCAAATACTTTCAGTAATCTGTCCCCTTATTTTTCCCAGTCTGTCCCCTTATTTTTCCCAGTGCCCGGACAAT