Basic Information
VIS ID
TVIS10010859
Fusion event
HBV-chr5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1786
Orient
-
Integrated sequence
AACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGT| |AGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
84367370/85071552 (Hg38)
End
84367370/85071552 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/2231328; hsa-mir-103a-1/Downstream/2043327;
Nearest TSS
ENST00000502646/Upstream/686073; ENST00000505572/Downstream/41204;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/686767, chr5-CpG: 34/Downstream/2195988
Nearby gene
EDIL3(-686759) ; NBPF22P(+1210892) ;
Upstream sequence
gtagatgataatagtgcatatgccatgtgattgtgatgagtaaatgatgtacctgcatgtaaactgtttatcacagtgcctgacacatatgctcaataca
Downstream sequence
GACAATATCTGAGACTCAAAAAGCTCTGCATTCTATTTCCCTATTCCTATTATTCCCACCTTAAGTGTAAGGAATCCATAAGAAAATAAGTCTACAATTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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