TRMT11 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010866
Fusion event
HBV-TRMT11 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2447
Orient
+
Integrated sequence
TTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCA| |ATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCC
Host Sequence
Chromosome
chr6
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
126314870/125993724 (Hg38)
End
126314870/125993724 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRMT11
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10398/Upstream/5978467; hsa-mir-1202/Downstream/490907;
Nearest TSS
ENST00000381078/Upstream/6810; ENST00000466316/Downstream/13118;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/6939, chr6-CpG: 27/Downstream/346265
Upstream sequence
tgatggaacCATTAAAAAATATGACTAGCACATTGGATCCAAAATAAATTGGCCCTTATGACCCTGAATGACACGTTGTTTTTTTTCTTCAGTGAACTAT
Downstream sequence
AATGTATTTTCTCTGTAATATTTTCAATACAGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAGTTTGCCAGCAGTCAAGAAACTTATGGAAAGGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate