Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010868
Fusion event
HBV-L3MBTL3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1822
Orient
-
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr6
Cytoband
q23.1
Reference genome
End
130410625/130089480 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/3604767; hsa-mir-1202/Downstream/1702692;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/68175, chr6-CpG: 134/Downstream/275789
Upstream sequence
tttgtatgggtagattttattgtttcagaaattttatgaagttcctaggaattggtcaataaccttgatctccctgatacgtcctggtataatgtagtca
Downstream sequence
gttggttccaggtctttgctattgtgaatagtgccgcaataaacatacatgtgcatgtgtctttatagtagcataatttataatcctttgggtatatatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.