Basic Information
VIS ID
TVIS10010877
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1263
Orient
-
Integrated sequence
CGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGC| |CGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATA
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
67055235/66345342 (Hg38)
End
67055235/66345342 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/8955130; hsa-mir-10524/Downstream/5031618;
Nearest TSS
ENST00000381078/Upstream/638117; ENST00000449928/Downstream/1543997;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/250404, chr6-CpG: 37/Downstream/2289498
Nearby gene
SLC25A51P1(-555859) ;
Upstream sequence
AATCTGTCACTGGTGTTTATTTGATCTGCAGAAAGGCTGGATTCATATGTCTTGCCATATTTCTGTGTTCTGAAGGGCAGTGAAACAGATTATCAAGGCC
Downstream sequence
GCCTGTGATTCTGTAGTTCCCATGGTTAGGTGACAAATAACTTCTTAGAcaggctccattaaaaaactattgaatcagagtttcttagaagtggggttta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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