Basic Information
VIS ID
TVIS10010878
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1633
Orient
-
Integrated sequence
CTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCAC| |CAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACT
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
88903473/88193754 (Hg38)
End
88903473/88193754 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6G
Nearest miRNA
hsa-mir-10398/Upstream/9654445; hsa-mir-1202/Downstream/2118988;
Nearest TSS
ENST00000381078/Upstream/27395; ENST00000354922/Downstream/227279;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/26024, chr6-CpG: 60/Downstream/769411
Nearby gene
CNR1(-27706) ; RNGTT(+416516) ;
Upstream sequence
CTGGTGTTTATTTGATCTGCAGAAAGGCTGGATTCATATGTCTTGCCATATTTCTGTGTTCTGAAGGGCAGTGAAACAGATTATCAAGGCCAAGTGTAAA
Downstream sequence
tcaaaatggaacaaagcaaacgtgaaattccgagtgtgcagagaggcaagactgcaacattaattttatgaggggactcttcagggcaataatatatcac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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