Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010880
Fusion event
HBV-CDHR3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
268
Orient
+
Integrated sequence
ACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTT| |CTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGG
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
End
105617445/105976999 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/3505468; hsa-mir-10399/Downstream/8676346;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/99482, chr7-CpG: 19/Downstream/32581
Upstream sequence
cacctgtaatcccagcttgtcaggaggctgaagaacgaggatcacttgaacccaggagtttgagaccagcctgggcagcatagtgagaccccatctcaaa
Downstream sequence
tgagatggggtctcactatgctgcccaggctgcacttgcattcctgggctcaagtgatcctctcgcctcagcctccccagtagctgagactacaggcact
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.