SLC26A3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010881
Fusion event
HBV-SLC26A3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2267
Orient
+
Integrated sequence
TCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTT| |CGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCC
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
107410668/107770223 (Hg38)
End
107410668/107770223 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC26A3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-7-5p ; hsa-mir-494-3p
Nearest miRNA
hsa-mir-10525/Upstream/5298692; hsa-mir-10399/Downstream/6883122;
Nearest TSS
ENST00000635602/Upstream/25642; ENST00000485066/Downstream/6529;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/25647, chr7-CpG: 51/Downstream/120812
Upstream sequence
aatagatgtgtgcagagtctctaaagactgggcttagaagtgccataacattacatctacggcattccattgggcagagaaagccacaagacaagcccag
Downstream sequence
ttttttttttttttttttttttttttttttttttttttttttttttgatttgagacagggtcttgctctgtcacccaggctagtgtgcagtggcacgatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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