Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010884
Fusion event
HBV-PDE1C integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
3101
Orient
+
Integrated sequence
ATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCC| |TCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
Start
End
31984754/31945142 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1183/Upstream/1655252; hsa-mir-10399/Downstream/787839;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/608214, chr7-CpG: 70/Downstream/125309
Upstream sequence
CACTGCACCATCGTCACTTAACACGATTTTACTTTGTTGCTGGACACATAACTCCTGCTTAAAATACTGTGGACATTGAGAACAGATTTGTATTATGCTA
Downstream sequence
ttataacagagtattcccaataagctgctctcatcccataggacattgctgtcattcatttcacttattcatatgctatgataacccaaaacattgatat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.