VISDB Viral Integration Site DataBase

VIS ID

TVIS10010895

Fusion event

HBV-CACNA2D1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

313

Orient

+

Integrated sequence

TTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATT| |CGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCAT

Chromosome

chr7

Cytoband

q21.11

Reference genome

Start

End

82018927/82389611 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1-3p ; hsa-mir-4642 ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4446-5p ; hsa-mir-6814-5p

Nearest miRNA

hsa-mir-10525/Upstream/6474342; hsa-mir-10399/Downstream/9814404;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/778219, chr7-CpG: 161/Downstream/53094

Upstream sequence

AGAACATATGTCACAGATGAAGAGTTGGTCCTAGTGCAAGTTTACAAATAAAAGACAAAGAACCTTTCAGCTATTGTGACTAGTTAGTCCCTTCTTTTAC

Downstream sequence

TAGCTGATGTACAGATTCGATGCCTCATTcttacttgatgtatgaccatagaaattccccatctctattagaaacccccagtctctgtttccccatcttt