Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010904
Fusion event
HBV-SGCZ integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
737
Orient
-
Integrated sequence
TCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGT| |TATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAA
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
Start
End
14733290/14875781 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-124-1/Upstream/22271; hsa-mir-10400/Downstream/2805797;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1598990, chr8-CpG: 87/Downstream/360947
Upstream sequence
gttgaacattccctttcgtagagtaggtttgaaaccctctttttatagtgtctggaagcgggcatttggagcgctttcaggcctatgctgaaaaaggaaa
Downstream sequence
gctatgttataaataaggagcctgaccttgaatagatgatttcacatctgggccacaatttagttggttgaaaaatggggataacatcaccctaatccaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.