VISDB Viral Integration Site DataBase

VIS ID

TVIS10010915

Fusion event

HBV-SNX16 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

480

Orient

-

Integrated sequence

GTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCT| |CTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAAC

Chromosome

chr8

Cytoband

q21.13

Reference genome

Start

End

82754700/81842465 (Hg38)

Orient

-

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-103a-3p ; hsa-mir-96-5p ; hsa-mir-16-5p ; hsa-mir-1277-5p ; hsa-mir-140-5p ; hsa-mir-195-5p ; hsa-mir-93-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-3927-5p ; hsa-mir-4519 ; hsa-mir-7849-3p ; hsa-mir-548e-5p ; hsa-mir-424-5p ; hsa-mir-6838-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-497-5p ; hsa-mir-4666a-3p

Nearest miRNA

hsa-mir-12123/Upstream/1600992; hsa-mir-10400/Downstream/9363020;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/224, chr8-CpG: 49/Downstream/2342059

Upstream sequence

AACTTGTCTCTCCAAATAAATAATATCATCCTGGATAACAAAGACTGTTTTATTCTCCTTCTCTTTTATTCCCCTCACACTGATCAGAGTGCTGGGTGTG

Downstream sequence

gacagagagagagagagagagagagagagagagagagagagagagagagagagagagagaaagagaaagaaaacgagcgagggagagagcgagagcgaga