VISDB Viral Integration Site DataBase

VIS ID

TVIS10010918

Fusion event

HBV-STK3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1804

Orient

-

Integrated sequence

ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC| |GCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT

Chromosome

chr8

Cytoband

q22.2

Reference genome

Start

End

99844497/98832269 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-141-3p ; hsa-mir-9-5p ; hsa-mir-128-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-133b

Nearest miRNA

hsa-mir-12123/Upstream/438531; hsa-mir-10400/Downstream/704367;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/6366, chr8-CpG: 214/Downstream/107523

Upstream sequence

tcacacctgtagtcacagcacttggggaggccaaggcaggaggatcacttgaggccaggaattcaagaccaggctgggcatcatagtgagacctcatctc

Downstream sequence

atagatatctatatatatattcacaaaggcagacactcacatgcacaataagcaaacatgcatattatatatgtcccatgttcactttggggtggagatt