VISDB Viral Integration Site DataBase

VIS ID

TVIS10010919

Fusion event

HBV-chr9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1764

Orient

-

Integrated sequence

CTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAA| |GGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTG

Chromosome

chr9

Cytoband

q22.33

Reference genome

Start

End

100362470/97600188 (Hg38)

Orient

+

Location type

UTR3

Target gene

TMOD1 ; TSTD2

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-412-3p ; hsa-mir-544a ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-2861 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-661 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-4512 ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-138-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4468 ; hsa-mir-4299 ; hsa-mir-6501-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-508-5p ; hsa-mir-4511

Nearest miRNA

hsa-let-7a-1/Upstream/236507; hsa-mir-12126/Downstream/628961;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/97253, chr9-CpG: 116/Downstream/32870

Upstream sequence

cctgggctccagcaaacctcccgcatcagcctccaagtagctagggctacaggcatgcatcagcaagcccagcttaaaaaaaaaaaatgctgtagagatg

Downstream sequence

TTAAAGTTGCCAAATTGATTACTGGATCCAGAACACAATTTTCCCCTCAGAACAGATAGACAGACTGAAGCCACTGAACTCTGCCAGGAGTCAACATGAG