Fusion event
HBV-chr9 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
CTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTT| |ACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATC
End
12079597/12079597 (Hg38)
Nearest miRNA
hsa-mir-101-2/Upstream/6071693; hsa-let-7a-1/Downstream/6493709;
Nearest cancer related gene
Upstream sequence
TCTTTCAGTGCTTCAGATTTGCTAGTAACCAGCTCTAAAAATTTATATGCAAAGAATTTACTTTTAGTTCTTCTATATCCATAGCAATATATATCATTTC
Downstream sequence
tcttcgaaggttttatggttttacgtctaatatatgagtctttaatccatcttgaattaatttttgtataaggtgtaaggaagggatccagtttcagctt
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.