Basic Information
VIS ID
TVIS10010926
Fusion event
HBV-chr9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
680
Orient
-
Integrated sequence
CTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTT| |ACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATC
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
End
12079597/12079597 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/6071693; hsa-let-7a-1/Downstream/6493709;
Nearby gene
PTPRD(-1466874) ; TYRP1(+613789) ;
Nearest cancer related gene
PTPRD(TSG, -1466874) ; TYRP1(OG, +613789) ;
Upstream sequence
TCTTTCAGTGCTTCAGATTTGCTAGTAACCAGCTCTAAAAATTTATATGCAAAGAATTTACTTTTAGTTCTTCTATATCCATAGCAATATATATCATTTC
Downstream sequence
tcttcgaaggttttatggttttacgtctaatatatgagtctttaatccatcttgaattaatttttgtataaggtgtaaggaagggatccagtttcagctt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate