VISDB Viral Integration Site DataBase

VIS ID

TVIS10010927

Fusion event

HBV-LRSAM1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1119

Orient

-

Integrated sequence

GCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCT| |TTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGT

Chromosome

chr9

Cytoband

q33.3

Reference genome

Start

End

130251307/127489028 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6810-3p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-7106-3p ; hsa-mir-4290 ; hsa-mir-4755-3p ; hsa-mir-1976 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6734-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-660-3p ; hsa-mir-5088-3p ; hsa-mir-4667-3p

Nearest miRNA

hsa-let-7a-1/Upstream/2795230; hsa-mir-12126/Downstream/201659;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/36972, chr9-CpG: 16/Downstream/19930

Upstream sequence

AACCAGCTCTAAAAATTTATATGCAAAGAATTTACTTTTAGTTCTTCTATATCCATAGCAATATATATCATTTCCAATATTTGTACTGTAAGTCCCAGTA

Downstream sequence

TTAGTATCTGTGGAGCTTGTCTGAGGAAAATTCTCCATTTCTCAGAGGAGGCATCTGCCTTGTGGTTAAGTGGGGCTCGGGAGCTGGATAGGCTTGGTGT