Basic Information
VIS ID
TVIS10010936
Fusion event
HBV-LINC01242 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
2
Orient
+
Integrated sequence
AA| |TTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACT
Host Sequence
Chromosome
chr9
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
30396486/30396488 (Hg38)
End
30396486/30396488 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA9C
Target gene
LINC01242
Nearest miRNA
hsa-mir-101-2/Upstream/1507533; hsa-let-7a-1/Downstream/2712204;
Nearest TSS
ENST00000422679/Upstream/1726202; ENST00000541043/Downstream/178524;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/569750, chr9-CpG: 62/Downstream/857465
Upstream sequence
AGGAACAGAACATCATTTACATATATAAAGAACAGCACGCTGTCTTCTTCCTTGAAGAGGAGCTGACCCTCCTCCCTGCTTGGCCATCATGCTCAGCCAT
Downstream sequence
tcctgaaaattttaaaaatatgttgaaattaaacaacatgctcctaaacaaccagtaggttatggaataaattaaaaggaaaatcaaagaataccttgag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate