VISDB Viral Integration Site DataBase

VIS ID

TVIS10010949

Fusion event

HBV-SYAP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2978

Orient

-

Integrated sequence

TCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGAC| |GCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTT

Chromosome

chrX

Cytoband

p22.2

Reference genome

Start

End

16743141/16725018 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-877-3p ; hsa-mir-22-5p ; hsa-mir-148a-5p ; hsa-mir-2116-5p ; hsa-mir-5002-5p ; hsa-mir-5584-3p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-4537 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4695-5p ; hsa-mir-4459 ; hsa-mir-5587-5p ; hsa-mir-6844 ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-133a-3p ; hsa-mir-133b ; hsa-mir-5698 ; hsa-mir-7641 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-4695-3p ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-6787-3p ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-6739-3p ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-3653-5p ; hsa-mir-5571-5p ; hsa-mir-4713-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-5193 ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-129-5p ; hsa-mir-510-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4313 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6832-3p ; hsa-mir-6887-3p ; hsa-mir-1285-5p ; hsa-mir-216a-5p ; hsa-mir-3672 ; hsa-mir-4499 ; hsa-mir-5187-3p ; hsa-mir-6864-3p ; hsa-mir-8055 ; hsa-mir-873-3p

Nearest miRNA

hsa-mir-3690-1/Upstream/97933; hsa-let-7f-2/Downstream/700863;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/5042, chrX-CpG: 124/Downstream/60738

Upstream sequence

ttagggttagggttagggttagggttagggttagggtgagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttag

Downstream sequence

tatcacataggacaaatcatttttcctctgtgagcctcagcttccctttttttgaactgggcagattattccttctccttgtcccaggaaggttatgaga