VISDB Viral Integration Site DataBase

VIS ID

TVIS10010951

Fusion event

HBV-SPIN3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1811

Orient

-

Integrated sequence

AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC

Chromosome

chrX

Cytoband

p11.21

Reference genome

Start

End

57013212/56986779 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-3156-3p ; hsa-mir-1260a ; hsa-mir-1260b ; hsa-mir-188-3p ; hsa-mir-27a-5p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-4301 ; hsa-mir-6814-5p ; hsa-mir-6777-3p

Nearest miRNA

hsa-let-7f-2/Upstream/1535197; hsa-mir-105-1/Downstream/6799223;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/422698, chrX-CpG: 34/Downstream/8379

Nearby gene

SPIN3(+4052) ;

Upstream sequence

agggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttaggggttagg

Downstream sequence

TTCCATTTAATCAGTGACCTCTTAGCCACTTTACTTGCTTTCTAGGATAACAATAGAAAAACATATTTAAggccgggcatggtgggacatgcctgtaatc