VISDB Viral Integration Site DataBase

VIS ID

TVIS10010953

Fusion event

HBV-MSN integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2240

Orient

-

Integrated sequence

CGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGA| |AACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACT

Chromosome

chrX

Cytoband

q12

Reference genome

Start

End

64866677/65646813 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-200c-3p ; hsa-mir-133a-3p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-615-3p ; hsa-let-7b-5p ; hsa-mir-200b-3p ; hsa-mir-6746-5p ; hsa-mir-30b-3p ; hsa-mir-6772-3p ; hsa-mir-3691-5p ; hsa-mir-3165 ; hsa-mir-3689d ; hsa-mir-6851-5p ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-6134 ; hsa-mir-4524a-3p ; hsa-mir-6770-5p ; hsa-mir-92a-2-5p ; hsa-mir-6748-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-4489 ; hsa-mir-4795-5p ; hsa-mir-664b-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-7113-5p ; hsa-mir-9500 ; hsa-mir-6824-5p ; hsa-mir-4536-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6731-5p ; hsa-mir-8085 ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-6783-5p ; hsa-mir-4779 ; hsa-mir-122-5p ; hsa-mir-1226-5p ; hsa-mir-1321 ; hsa-mir-144-3p ; hsa-mir-1914-3p ; hsa-mir-2467-5p ; hsa-mir-3126-5p ; hsa-mir-3144-5p ; hsa-mir-3148 ; hsa-mir-3151-5p ; hsa-mir-3191-3p ; hsa-mir-338-3p ; hsa-mir-4419a ; hsa-mir-4424 ; hsa-mir-4433b-3p ; hsa-mir-4435 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4510 ; hsa-mir-4530 ; hsa-mir-4534 ; hsa-mir-4652-5p ; hsa-mir-4716-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-5194 ; hsa-mir-574-5p ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-615-5p ; hsa-mir-625-5p ; hsa-mir-651-3p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6742-5p ; hsa-mir-6794-5p ; hsa-mir-6796-5p ; hsa-mir-6798-5p ; hsa-mir-6800-5p ; hsa-mir-6802-5p ; hsa-mir-6810-5p ; hsa-mir-6822-3p ; hsa-mir-6830-5p ; hsa-mir-6834-5p ; hsa-mir-6875-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-766-3p ; hsa-mir-8065 ; hsa-mir-2115-5p ; hsa-mir-3185 ; hsa-mir-345-3p ; hsa-mir-4725-5p

Nearest miRNA

hsa-let-7f-2/Upstream/1860726; hsa-mir-105-1/Downstream/372057;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/94500, chrX-CpG: 29/Downstream/20804

Nearby gene

FRMD8P1(-94376) ; MSN(+20834) ;

Upstream sequence

GTGGTTAATAGAGACACAGTTCCAAAACAGATTATACCAATAGTTTGAGTCTCTAGCAACACCAAACTGGGGCTTATCCCCAAACCAGGCTTGTGCTTCA

Downstream sequence

gtgcatgcctgtaatcccagctactcgagaggctgaggcaggagaatctcttgaacccggggagcggaggttgtggtgagccgagatcgcaccattgcac