VISDB Viral Integration Site DataBase

VIS ID

TVIS10010954

Fusion event

HBV-MSN integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

39

Orient

+

Integrated sequence

AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGA| |GTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTG

Chromosome

chrX

Cytoband

q12

Reference genome

Start

End

64870995/65651131 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-200c-3p ; hsa-mir-133a-3p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-615-3p ; hsa-let-7b-5p ; hsa-mir-200b-3p ; hsa-mir-6746-5p ; hsa-mir-30b-3p ; hsa-mir-6772-3p ; hsa-mir-3691-5p ; hsa-mir-3165 ; hsa-mir-3689d ; hsa-mir-6851-5p ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-6134 ; hsa-mir-4524a-3p ; hsa-mir-6770-5p ; hsa-mir-92a-2-5p ; hsa-mir-6748-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-4489 ; hsa-mir-4795-5p ; hsa-mir-664b-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-7113-5p ; hsa-mir-9500 ; hsa-mir-6824-5p ; hsa-mir-4536-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6731-5p ; hsa-mir-8085 ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-6783-5p ; hsa-mir-4779 ; hsa-mir-122-5p ; hsa-mir-1226-5p ; hsa-mir-1321 ; hsa-mir-144-3p ; hsa-mir-1914-3p ; hsa-mir-2467-5p ; hsa-mir-3126-5p ; hsa-mir-3144-5p ; hsa-mir-3148 ; hsa-mir-3151-5p ; hsa-mir-3191-3p ; hsa-mir-338-3p ; hsa-mir-4419a ; hsa-mir-4424 ; hsa-mir-4433b-3p ; hsa-mir-4435 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4510 ; hsa-mir-4530 ; hsa-mir-4534 ; hsa-mir-4652-5p ; hsa-mir-4716-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-5194 ; hsa-mir-574-5p ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-615-5p ; hsa-mir-625-5p ; hsa-mir-651-3p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6742-5p ; hsa-mir-6794-5p ; hsa-mir-6796-5p ; hsa-mir-6798-5p ; hsa-mir-6800-5p ; hsa-mir-6802-5p ; hsa-mir-6810-5p ; hsa-mir-6822-3p ; hsa-mir-6830-5p ; hsa-mir-6834-5p ; hsa-mir-6875-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-766-3p ; hsa-mir-8065 ; hsa-mir-2115-5p ; hsa-mir-3185 ; hsa-mir-345-3p ; hsa-mir-4725-5p

Nearest miRNA

hsa-let-7f-2/Upstream/1865044; hsa-mir-105-1/Downstream/367739;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/98818, chrX-CpG: 29/Downstream/16486

Nearby gene

FRMD8P1(-98694) ; MSN(+16516) ;

Upstream sequence

gcatttgagttggttccaagtctttgctattgtaaatagtgctgcaataaacatacaggtacatgtgtctttatagtagaatgatttataatcctttggg

Downstream sequence

aattagAggccgggtgcagtggctcatgcctgtaattccagcactttgggaggctgaggtaggcagatcacttgagttcaagcgtttgagaccagccttg