Basic Information
VIS ID
TVIS10010957
Fusion event
HBV-CHMP1B2P integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
680
Orient
-
Integrated sequence
CTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTT| |ACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATC
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
79550624/80295125 (Hg38)
End
79550624/80295125 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHMP1B2P
Nearest miRNA
hsa-let-7f-2/Upstream/1393876; hsa-mir-105-1/Downstream/3930627;
Nearest TSS
ENST00000429181/Upstream/272056; ENST00000538312/Downstream/40379;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2155330, chrX-CpG: 27/Downstream/40096
Nearby gene
TBX22(-263356) ; TENT5D(+40379) ;
Upstream sequence
gtcttgcaggcctttgtgttttactcttagagatataaggaatcaTAATTCTGgaacagaatgctgagaaactcccatatttagaggcctggaaaagatg
Downstream sequence
acctagacaataccattcaggacataggcatgggcaaggacttcatgtctaaaacaccaaaagcaatggcaacaaaagccaaaattgacaaatgggatct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate