Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010969
Fusion event
HBV-DAB1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2479
Orient
-
Integrated sequence
ACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGG| |AACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAA
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
Start
End
58357395/57891723 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/2666000; hsa-mir-101-1/Downstream/1841504;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/466758, chr1-CpG: 87/Downstream/357877
Upstream sequence
atagactggataaagaaaatgtggcaccatggaatactatgaagccataaaaaggatgagttcatgtcctttgcaggaacatggatgaagctggaggcta
Downstream sequence
tcatgctcaacaaacacaggagcagaaaaccaaacatctcatgttctcactcataagtgggagttgaacaaagagaacacatggacacagggaggggaac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.