Basic Information
VIS ID
TVIS10010972
Fusion event
HBV-LINC01909 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1577
Orient
-
Integrated sequence
GGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGAC| |CGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTC
Host Sequence
Chromosome
chr18
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
68015349/70348113 (Hg38)
End
68015349/70348113 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC01909
Nearest miRNA
hsa-mir-1-2/Upstream/3266427; hsa-mir-548av/Downstream/2505208;
Nearest TSS
ENST00000575820/Upstream/10803; ENST00000563639/Downstream/36478;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/58287, chr18-CpG: 21/Downstream/82457
Nearby gene
SOCS6(-17915) ; LINC01541(+1171851) ;
Upstream sequence
gaggcgctctgatttttagaatttctagcttttctgctctgtttttccccatctttgtggttttatctacctttgatctttgatgatggtgacgtacaga
Downstream sequence
tggcgttttggtgtggatatcctttctgtttgttagttttccttctaacagtcaggaccttcagctgcaggtctgttggagtttgctggaggtccactcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate