hsa-mir-422a _LIHC.png
TERT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010978
Fusion event
HBV-TERT integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1818
Orient
-
Integrated sequence
GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
End
1295173/1295058 (Hg38)
Orient
+
Location type
upstream
Target gene
Nearest miRNA
hsa-mir-4635/Upstream/232084; hsa-mir-10397/Downstream/14252;
Nearest CpG islands
chr5-CpG: 485/Target, None/Upstream, None/Downstream
Nearest cancer related gene
TERT(OG, No orient, 0)
Upstream sequence
TTTTATATAAAGATTTACTCAAATAAgtcttagcatgaggtttccaggaaggaggcagtgagataagaagagaaatgcaagtggttaattagggagatgc
Downstream sequence
GCGAGGAGAgggcggggccgcggaaaggaaggggaggggctgggagggcccggagggggctgggccggggacccgggaggggtcgggacggggcggggtc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate