Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010988
Fusion event
HBV-HVCN1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1479
Orient
-
Integrated sequence
CTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGG| |GACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCG
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
End
111093712/110655907 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7i/Upstream/822471; hsa-mir-1178/Downstream/648235;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/41562, chr12-CpG: 58/Downstream/32899
Upstream sequence
aattctcccacttcagcctcccgagtagctgggataacaggcacgtaccaccatgcctggctaatttttgtatttttagtagagatggtgtttcaccatg
Downstream sequence
ttagccaggctggtctcgagctcctaaccccaagtgatccacccaccttggcctcccaaagtgctgggattacaggcataagccaccgtgcccagGCAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.