VISDB Viral Integration Site DataBase

VIS ID

TVIS10010998

Fusion event

HBV-KHDRBS2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1775

Orient

+

Integrated sequence

TCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTAC| |TAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCC

Chromosome

chr6

Cytoband

q11.1

Reference genome

Start

End

62691874/61981969 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p

Nearest miRNA

hsa-mir-10398/Upstream/4591757; hsa-mir-10524/Downstream/9394991;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/4020419, chr6-CpG: 45/Downstream/303981

Upstream sequence

AAACCCATTTTTGTCACGTGTGTGTGCTGAAAGTAACTAAGAGGTTAAATCAGTTATCATACTTGTTAAAATTATGCAACCAGCAAAATATGCAAGTGAG

Downstream sequence

ccataaattaaatattgtattccacagaaaccaccaaaatcctttgtcaactgtgttataatgaattcacgtcagatatttaacatagccattttaagct