Basic Information
VIS ID
TVIS10011000
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
3087
Orient
+
Integrated sequence
GTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAA| |ATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
End
73986024/73520341 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/2452625; hsa-mir-11399/Downstream/3539802;
Nearby gene
NEGR1(-1237747) ; LRRIQ3(+505678) ;
Upstream sequence
TCAAATGGTgattgatctgcctacaggaataaaaatcaataatctttaaaataagataacagaattgaatcctttacaacatatcaacaatagccatatg
Downstream sequence
ccaaaaaaaaaaacaaaattaccagacatagaaaactaataaaacacaacaggaaaatattgcccaaagaaggaaaaaggtagttaatagcaaagaatct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate