Basic Information
VIS ID
TVIS10011015
Fusion event
HBV-CEP128 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
End
81239082/80772738 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1260a/Upstream/3506448; hsa-mir-1185-1/Downstream/13175488;
Upstream sequence
gtcacagacacccacgcctggatgctactgtggggctggatcccagaggtagttgccccaactcctgcacctgccaatctgtgtgctccccctcccataa
Downstream sequence
gaggtttcagtgtgcatggcagcccaacagacaagccacaaccctgttgcacatcctgcaaggggggtcagggaactctctcctctcaTTACCAGCTTTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate