VISDB Viral Integration Site DataBase

VIS ID

TVIS10011016

Fusion event

HBV-CEP128 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1828

Orient

-

Integrated sequence

AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT

Chromosome

chr14

Cytoband

q31.1

Reference genome

Start

End

81239159/80772815 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-10a-5p ; hsa-mir-6755-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-4762-5p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa

Nearest miRNA

hsa-mir-1260a/Upstream/3506525; hsa-mir-1185-1/Downstream/13175411;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/910827, chr14-CpG: 29/Downstream/168551

Upstream sequence

tctgtgtgctccccctcccataagaggtttcagtgtgcatggcagcccaacagacaagccacaaccctgttgcacatcctgcaaggggggtcagggaact

Downstream sequence

ctctcctctcaTTACCAGCTTTGTCTCAGTAGTCCAGTGCTACCGTGTAAACTCTGAGACAATGCTTGTTAAACAAAAGGTAATACGTAGATTTTTCAGG