VISDB Viral Integration Site DataBase

VIS ID

TVIS10011029

Fusion event

HBV-MEMO1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2794

Orient

+

Integrated sequence

TAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACA| |ACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCC

Chromosome

chr2

Cytoband

p22.3

Reference genome

Start

End

32151376/31926307 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4642 ; hsa-mir-580-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-3649 ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-645 ; hsa-mir-4442 ; hsa-mir-3687 ; hsa-mir-4712-3p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-4797-5p ; hsa-mir-3929 ; hsa-mir-324-5p ; hsa-mir-129-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-4477a ; hsa-mir-2115-5p

Nearest miRNA

hsa-mir-1301/Upstream/3929858; hsa-mir-10b/Downstream/605846;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/344594, chr2-CpG: 174/Downstream/83277

Upstream sequence

ataaatttttaaaaaatagccaggcatgctggcacaggctggcagtcctagctactcagaaggctggaataggaggatcacttgagcctgggaattcaac

Downstream sequence

gctgcgtgagctatgatcatgccactgactccagactgggtgacagagcaagatcctgtctcaaaagggaaaaaaaaaaaaaaaaacagaatctagcact