VISDB Viral Integration Site DataBase

VIS ID

TVIS10011046

Fusion event

HBV-FUT9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2236

Orient

-

Integrated sequence

CCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAA| |GAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGA

Chromosome

chr6

Cytoband

q16.1

Reference genome

Start

End

96604358/96156482 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-7703 ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-767-5p ; hsa-mir-4486 ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-939-3p ; hsa-mir-6850-3p ; hsa-mir-1273g-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-186-3p ; hsa-mir-576-3p ; hsa-mir-3121-3p

Nearest miRNA

hsa-mir-10398/Upstream/4634745; hsa-mir-1202/Downstream/1868049;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/140222, chr6-CpG: 61/Downstream/365153

Upstream sequence

attaagggtcttggaccgtatttcctgtgggtaaagggaaactactgTACTGACCACTGAAAGCAATTGTTCTTTTATCTATTTTTATTTGTAAAAATAA

Downstream sequence

gttttccttcgcagtacaagggcttatatatatataagctgatggagctgggttccctatttgtataaggcataaattccaggtggctctgccccattcc