VISDB Viral Integration Site DataBase

VIS ID

TVIS10011059

Fusion event

HBV-ASH1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2222

Orient

+

Integrated sequence

TTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTG| |TCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTA

Chromosome

chr1

Cytoband

q22

Reference genome

Start

End

155360252/155390461 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-625-5p ; hsa-mir-193b-3p ; hsa-mir-361-5p ; hsa-mir-185-5p ; hsa-mir-17-5p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-214-3p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-548t-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-6864-5p ; hsa-mir-4696 ; hsa-mir-3179 ; hsa-mir-154-5p ; hsa-mir-302f ; hsa-mir-5692a ; hsa-mir-6083 ; hsa-mir-374b-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-3140-3p ; hsa-mir-4729 ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-656-3p ; hsa-mir-646 ; hsa-mir-651-3p ; hsa-mir-503-5p ; hsa-mir-15b-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-107 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-718 ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-138-2-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-627-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-183-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-377-3p ; hsa-mir-3650 ; hsa-mir-3665 ; hsa-mir-3934-5p ; hsa-mir-4705

Nearest miRNA

hsa-mir-101-1/Upstream/44016; hsa-mir-1182/Downstream/560812;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/64819, chr1-CpG: 95/Downstream/172034

Upstream sequence

aaaaaatttcagttctaaatggcttccctagtgaagtctggtatatgtttgagaaagaagtaataccagtcttccagaaaacagaggaggaaaataattt

Downstream sequence

tccaactcatttaatgaagctagtgtatgcctaatacaaaacttgacaaagactttaaaagaaaaaacaactatagaacaaAATTaattctaaagacttc