VISDB Viral Integration Site DataBase

VIS ID

TVIS10011077

Fusion event

HBV-SCN4B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2418

Orient

+

Integrated sequence

CCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGT| |CGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTT

Chromosome

chr11

Cytoband

q23.3

Reference genome

Start

End

118024387/118153672 (Hg38)

Orient

-

Location type

upstream

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-122-5p ; hsa-mir-1225-3p ; hsa-mir-1233-3p ; hsa-mir-214-3p ; hsa-mir-3619-5p ; hsa-mir-4299 ; hsa-mir-4471 ; hsa-mir-4530 ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-582-3p ; hsa-mir-657 ; hsa-mir-761 ; hsa-mir-7855-5p ; hsa-mir-8059

Nearest miRNA

hsa-mir-10392/Upstream/4703584; hsa-let-7a-2/Downstream/490328;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/193, chr11-CpG: 22/Downstream/205777

Upstream sequence

CCATGGACCCCTTGGAAATCACCACGCTCCAGGTTAGGGAGCAGGTTGGTCCGCGCCTGGTCTGTGTCCTGCGCCCCATTTCACCCTCCCGCTGCACCCC

Downstream sequence

TGCTTCTCATTTTTCCTACCTAGGCCGTCCCCCTCAGATGCTGCCTTTTCGCCCTCCTCCAACTCTCCTGTTTTCTTCGGAACGGCAGACTCCCTCGGCC