Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011078
Fusion event
HBV-MPZL2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2722
Orient
-
Integrated sequence
AAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTT| |AATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCAC
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
End
118125981/118255266 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/4805178; hsa-let-7a-2/Downstream/388734;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/101787, chr11-CpG: 22/Downstream/104183
Upstream sequence
CAAAGAAAAGTTTCCATTAACTTCAAGAAATACTAGGGTTCTTGTTCTTGGAAATCATCTCAGCTTCCTAAAACACAAAACAAAAGTTTAAATGGATAAT
Downstream sequence
ATATTTGAGAAGAGTACAATAGGAATACTTGGCATTATGAATTACATATATGTTATTAGAAGGAAAATATTCTGAGGGAAAGTATTCATATTCTCCCCCA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.