Fusion event
HBV-chr11 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
CTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTC| |AGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATG
End
27856773/27835226 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/320179; hsa-let-7a-2/Downstream/221589;
Upstream sequence
TAGGAGCAACGCACCTTGGTTTTCACAGTCTAATTGAAAAGAAAACGATTTCACATTTAAAAAATGAAATAACATGAAGTAACAGTAAAATCCCTCATCA
Downstream sequence
TAGTTTATTTATTCATGTAACATTTAATTAATTAATTAAtttatttatttattttttatggagtctcctctgtcacccaggttggaatgcaatggtgcga
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.