Basic Information
VIS ID
TVIS10011082
Fusion event
HBV-LINC02741 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1760
Orient
-
Integrated sequence
AGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGT| |TAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCT
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
GRCh37/hg19
Start
41726296/41704746 (Hg38)
End
41726296/41704746 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02741
Nearest miRNA
hsa-mir-1343/Upstream/5694542; hsa-let-7a-2/Downstream/1854910;
Nearest TSS
ENST00000527297/Upstream/244973; ENST00000530379/Downstream/7662;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/5194279, chr11-CpG: 49/Downstream/1607143
Nearby gene
LRRC4C(-245110) ; LINC02740(+482997) ;
Upstream sequence
tcaagactgacccaaagggatggcattgatggcctctcttgatttctgtctttcagaagagttaggccaatgggaaataccaacacgaaaatgaaagaaa
Downstream sequence
ggaggatcaaaaggttgaaatatttttttccAATGTAGTAGCTATGACTGGCCCCATCCACAAATGAAAAGCCATGGCTCCTGTTGGGTGACTTTCCACA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate