VISDB Viral Integration Site DataBase

VIS ID

TVIS10011089

Fusion event

HBV-CCT2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2606

Orient

+

Integrated sequence

GTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCA| |CAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTA

Chromosome

chr12

Cytoband

q15

Reference genome

Start

End

69996081/69602301 (Hg38)

Orient

-

Location type

downstream

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-193b-3p ; hsa-mir-144-3p ; hsa-mir-539-5p ; hsa-mir-607 ; hsa-mir-3646 ; hsa-mir-3671 ; hsa-mir-5680 ; hsa-mir-4712-3p ; hsa-mir-5700

Nearest miRNA

hsa-let-7i/Upstream/17478; hsa-mir-1178/Downstream/9816956;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/16357, chr12-CpG: 139/Downstream/136259

Upstream sequence

tttcgagtaggtgggattacatggtagtccaccaccatgcccggctaatttttgtatttttagtagagaatgggattttgccatgttggccaggctggtc

Downstream sequence

tcTATGTTGTATGATGTTTTTAAGCTTGAAAAAGTCATATTTTAAAGTTGCAAGATGATGTGCTCTAAGTATCtttttttttcaagacaggatctcactc