VISDB Viral Integration Site DataBase

VIS ID

TVIS10011123

Fusion event

HBV-ACAA1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1819

Orient

-

Integrated sequence

TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA

Chromosome

chr3

Cytoband

p22.2

Reference genome

Start

End

38169341/38127850 (Hg38)

Orient

-

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-10a-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-mir-12127/Upstream/158370; hsa-let-7g/Downstream/1010356;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/88154, chr3-CpG: 54/Downstream/8661

Upstream sequence

GGAACTACTGCAGAGCTATTGAAAGAAAAGCTATGGTGTTCTGAACTTAAAATTCCCTCCCTAAAATTGCTATGAGCTCTAATTTCAGTCTCTTTCCTAC

Downstream sequence

ATTCTCAGAGGTTATCCTAGAACACAAACAGCAGATAGTGTGGGCATTGGTCTGACAGCCTAGAGGAAGGGACCAGGCTGTAGAGCTGTGCTTGGAACTT