Basic Information
VIS ID
TVIS10011125
Fusion event
HBV-LINC00877 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1805
Orient
-
Integrated sequence
TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
GRCh37/hg19
Start
72142619/72093468 (Hg38)
End
72142619/72093468 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC00877
Nearest miRNA
hsa-let-7g/Upstream/551379; hsa-mir-12124/Downstream/3121008;
Nearest TSS
ENST00000440867/Upstream/8827; ENST00000469178/Downstream/6644;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/307966, chr3-CpG: 116/Downstream/353234
Nearby gene
PROK2(-308262) ; LINC00870(+57789) ;
Upstream sequence
cttgggagggttaagagcaatcatgatgaatgaggggtctggcctctcactttctggatgtggtgatctggtgggtttcagttctttgatactttttgag
Downstream sequence
gccccataaggcaaccacaaaacacctcaaaatgcaaaaagctttactatgtagaagtattaGTGAGCCTTAAAAGCTGAAAGTTTGAAAAGATGTAAAC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate